Maus II begins right where Maus I stopped, both Vladeek and Anja arrive at Auschwitz and are given prisoner uniforms. Their heads are shaved and they are stripped of all clothing. All articles they brought with them would be destroyed or stolen. They were filed into a housing district and they soon discovered the horrors they would have to survive. The bedding was thin, the food was stale, the sanitation was poor, it was hell. They are forced to work all day and many prisoner mice die from exhaustion.
Vladek gets a special luck of the dice when he figures out he can teach a head guard English in return for favors and bonuses. He knows English well and teaches the guard the language throughout his stay. He gets better food and better clothing than the other prisoners because of it. We then find out that the author cannot get himself to finish the book ,but is reassured by himself that no one suffered more than the people at Auschwitz and therefore he must persevere.
He continues with the story and Anja gets taken to another camp, this one is for Jewish people who are about to be murdered. He makes his way over to the camp where he is then beaten by Nazis and put into a hospital. He then tells Art that he was inspected by the Angel of Death but nothing came of it and he later fell ill and was shipped to Switzerland as a prisoner of war. When American soldiers rescue him he finally gets to be reunited with his wife. In the end Art gets mistaken by Vladek who is very sick and thinks Art is someone else.